Table 1 Patient Characteristics
Variable | CT + B (n = 114) n (%) | CT (n = 123) n (%) |
|---|---|---|
Median age, years (range) | 66 (34–83) | 67 (37–82) |
Gender | ||
Male | 70 (61.4) | 74 (60.2) |
Female | 44 (38.6) | 49 (39.8) |
Performance status (ECOG) | ||
0 | 97 (85.1) | 102 (82.9) |
1 | 17 (14.9) | 21 (17.1) |
Tumor localization | ||
Rectum | 31 (27.2) | 34 (27.6) |
Colon | 83 (72.8) | 89 (72.4) |
Histology | ||
Adenocarcinoma | 104 (91.2) | 119 (96.8) |
Mucinous adenocarcinoma | 10 (8.8) | 4 (3.2) |
Grade | ||
1 | 0 | 0 |
2 | 56 (64.4) | 67 (65.1) |
3 | 31 (35.6) | 36 (34.9) |
Unknown | 27 | 20 |
Stage at diagnosis | ||
I–III | 29 (26.4) | 31 (27.2) |
IV | 81 (73.4) | 83 (72.8) |
Unknown | 4 | 9 |
Chemotherapy regimen planned | ||
FOLFOX4 | 69 (60.5) | 73 (59.4) |
FOLFIRI | 45 (39.5) | 50 (40.6) |
KRAS statusa | ||
Wild type | 67 (59.8) | 69 (58.5) |
Mutated | 45 (40.2) | 49 (41.5) |
Unknown | 2 | 5 |
Prior cancer therapy | ||
Surgery | 88 (77.2) | 91 (74.0) |
Radiotherapy | 11 (9.6) | 11 (8.9) |
Adjuvant chemotherapy | 18 (15.8) | 17 (13.8) |