Effect of deworming on Th2 immune response during HIV-helminths co-infection

Table 2 Summary of demographic characteristics and immunological indices

Characteristics	Symptomatic HIV infection (N = 60)	Asymptomatic HIV infection (N = 45)	Healthy controls (N = 25)
Males	28	19	17
Females	32	26	8
Mean age (years)	30.6 ± 8	29.0 ± 9	26.5 ± 7
Median (IQR) total serum IgE (IU/ml)
With helminths	1,593 (1,132–2,497)^b	1,231 (706–2,241)^c	908 (401–1,625)
Without helminths	1,259 (625–2,256)	831 (628–1,617)	662 (127–875)
Median (IQR) CD4⁺ T cells count (cells/mm³ of blood)
With helminths	169 (48–201)	555 (128–672)^a	707 (98–1,003)
Without helminths	161 (39–218)	677 (190–879)	792 (91–1,129)
Median (IQR) CD8⁺ T cells count (cells/mm³ of blood)
With helminths	1,070 ± 103^d	1,009 ± 82	1,072 ± 96
Without helminths	869 ± 87	813 ± 71	893 ± 84

^aSignificant difference compared to asymptomatic group without helminths and symptomatic group with helminths, P < 0.05.
^bSignificant difference compared to asymptomatic group with helminths and symptomatic group without helminths, P < 0.01.
^cSignificant difference compared with asymptomatic group without helminths, P < 0.01.
^dSignificant difference compared to symptomatic and asymptomatic group without helminths, P < 0.01.

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