Parameters | Gr | Liver | Kidney | Heart | Brain | Testes |
---|---|---|---|---|---|---|
ROS production (nmol DCF/min/mg of protein) | I | 28.65 ± 1.67 | 38.15 ± 2.24 | 28.15 ± 2.02 | 33.49 ± 2.23 | 31.49 ± 1.54 |
II | 78.56 ± 3.92# | 86.29 ± 3.48# | 64.13 ± 3.69# | 67.09 ± 5.12# | 71.23 ± 4.28# | |
III | 53.47 ± 2.67** | 66.50 ± 4.54** | 49.95 ± 3.15* | 50.21 ± 3.85* | 52.15 ± 3.94** | |
IV | 59.33 ± 3.45** | 71.18 ± 4.12* | 51.78 ± 3.88* | 52.33 ± 3.08* | 56.01 ± 3.42* | |
Lipid peroxidation (TBARS level in μg/g of tissue) | I | 5.11 ± 0.76 | 8.76 ± 1.01 | 4.21 ± 0.58 | 2.34 ± 0.32 | 3.22 ± 0.32 |
II | 8.74 ± 0.98# | 16.15 ± 2.11# | 8.25 ± 0.58# | 4.12 ± 0.50# | 5.58 ± 0.72# | |
III | 5.86 ± 0.54* | 10.24 ± 1.54* | 5.02 ± 0.45** | 2.67 ± 0.24* | 3.61 ± 0.42* | |
IV | 5.94 ± 0.72* | 10.58 ± 1.33* | 5.21 ± 0.62* | 2.86 ± 0.33* | 3.78 ± 0.45* | |
Protein cabonylation (nmol/mg of protein) | I | 34.56 ± 1.89 | 4.87 ± 0.54 | 2.31 ± 0.22 | 1.92 ± 0.34 | 1.02 ± 0.12 |
II | 72.13 ± 2.67# | 9.76 ± 1.01# | 5.02 ± 0.51# | 3.87 ± 0.56$ | 1.97 ± 0.23# | |
III | 41.32 ± 2.01** | 6.65 ± 0.67* | 3.28 ± 0.33* | 2.24 ± 0.48* | 1.32 ± 0.09* | |
IV | 44.56 ± 2.11** | 6.89 ± 0.78* | 3.41 ± 0.42* | 2.29 ± 0.31* | 1.38 ± 0.14* | |
NADPH oxidase (pmol/min/mg of protein) | I | 0.42 ± 0.03 | 0.56 ± 0.04 | 0.67 ± 0.03 | 0.38 ± 0.02 | 0.32 ± 0.03 |
II | 3.67 ± 0.55# | 4.55 ± 0.67# | 3.91 ± 0.40# | 2.98 ± 0.33# | 3.18 ± 0.28# | |
III | 2.45 ± 0.18* | 2.85 ± 0.33* | 2.44 ± 0.45* | 1.85 ± 0.24* | 2.24 ± 0.35* | |
IV | 2.58 ± 0.21* | 2.89 ± 0.54* | 2.58 ± 0.32* | 1.89 ± 0.27* | 2.38 ± 0.26 | |
Total coenzyme Q9 (nmol/g of wet tissue) | I | 178.67 ± 9.14 | 148.32 ± 6.33 | 58.24 ± 3.98 | 28.67 ± 1.72 | 98.72 ± 4.92 |
II | 124.56 ± 7.33# | 112.56 ± 5.59# | 39.21 ± 2.21# | 17.87 ± 1.08# | 66.67 ± 3.90# | |
III | 164.43 ± 8.39** | 144.06 ± 6.18** | 53.12 ± 2.92* | 24.41 ± 1.45* | 84.56 ± 4.04* | |
IV | 158.25 ± 7.53* | 139.33 ± 5.89* | 49.32 ± 2.54 | 24.18 ± 1.52* | 81.31 ± 3.78 | |
Total coenzyme Q10 (nmol/g of wet tissue) | I | 30.50 ± 2.34 | 25.67 ± 1.92 | 27.24 ± 1.98 | 7.51 ± 0.46 | 14.21 ± 1.02 |
II | 18.72 ± 1.78# | 15.70 ± 1.18# | 18.67 ± 1.02# | 4.35 ± 0.22# | 8.67 ± 0.84# | |
III | 28.33 ± 1.98** | 23.65 ± 1.78** | 24.89 ± 1.54* | 6.12 ± 0.52* | 12.33 ± 1.10* | |
IV | 27.65 ± 2.12* | 22.04 ± 1.04* | 24.10 ± 1.42 | 5.78 ± 0.42 | 11.75 ± 0.78 |