Fig. 6From: MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancerMiR-106b enhances radioresistance by targeting PTEN and p21. miR-106b upregulation downregulates PTEN and p21 and subsequently enhances radioresistance. p21 functioned as a DNA damage repair promoter at “a relatively normal level” of miR-106b and PI3K/AKT, while it acted as a DNA damage repair inhibitor when altering miR-106b expression.Back to article page