Fig. 5
From: MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer
PTEN expression is inversely related to that of miR-106b in colorectal cancer. a A western blot for the PTEN protein was performed in colorectal cancer cell lines. b qRT-PCR on 15 colorectal cancer patients. The association between miR-106b and PTEN mRNA for the 15 subjects in the tumour class and for the paired 15 subjects in the normal class was statistically calculated using the Spearman correlation coefficient (p = 0.006, Spearman’s r = −0.491). The Spearman correlation indicated an inverse relation between miR-106b and PTEN mRNA in the normal and tumour samples.