|  | 11 days | 21 days | p values vs ctrl |
---|---|---|---|---|
Autologous ASCs (n = 14) | Epithelial regeneration | 3 (2–3) | 3 (3–3) | p < 0.001 |
Inflammatory infiltrate | 2 (1–2) | 1 (1–2) | p < 0.001 | |
Collagen deposition | 2 (2–3) | 3 (2–3) | p < 0.001 | |
PCNA-positive nuclei | ||||
 Epidermis | 3 (1–3) | 3 (2–3) | p < 0.001 | |
 Dermis | 2 (1–3) | 2 (2–3) | ||
Allogeneic ASCs (n = 9) | Epithelial regeneration | 2 (2–2) | 1 (1–1) | p < 0.001 |
Inflammatory infiltrate | 2 (2–3) | 2 (2–3) | p = 0.039 | |
Collagen deposition | 2 (2–2) | 2 (2–2) | p < 0.001 | |
PCNA-positive nuclei | ||||
 Epidermis | 2 (1–3) | 2 (1–2) | p < 0.01 | |
 Dermis | 2 (2–3) | 2(2–3) | ||
BM-MSCs (n = 4) | Epithelial regeneration | 1 (1–2) | 1 (1–1) | p < 0.001 |
Inflammatory infiltrate | 3 (2–3) | 3 (3–3) | p = 0.99 | |
Collagen deposition | 1 (0–2) | 1 (1–1) | p = 0.43 | |
PCNA-positive nuclei | ||||
 Epidermis | 1 (1–2) | 2 (2–2) | p < 0.01 | |
 Dermis | 2 (2–3) | 2 (2–2) | ||
Control wounds (n = 27) | Epithelial regeneration | 0 (0–1) | 1 (0–1) |  |
Inflammatory infiltrate | 3 (3–3) | 3 (2–3) |  | |
Collagen deposition | 0 (0–1) | 1 (1–2) | ||
PCNA-positive nuclei | ||||
 Epidermis | 0 (0–1) | 3 (2–3) | ||
 Dermis | 0 (0–1) | 3 (3–3) |