Table 2 Semi-quantitative assessment of the regenerated epithelial layer features, inflammatory infiltrate extent, collagen deposition and PCNA-positive nuclei in differently treated wounds at 11 and 21 days

Autologous ASCs (n = 14)

Epithelial regeneration

3 (2–3)

3 (3–3)

p < 0.001

Inflammatory infiltrate

2 (1–2)

1 (1–2)

p < 0.001

Collagen deposition

2 (2–3)

3 (2–3)

p < 0.001

PCNA-positive nuclei

 Epidermis

3 (1–3)

3 (2–3)

p < 0.001

 Dermis

2 (1–3)

2 (2–3)

Allogeneic ASCs (n = 9)

Epithelial regeneration

2 (2–2)

1 (1–1)

p < 0.001

Inflammatory infiltrate

2 (2–3)

2 (2–3)

p = 0.039

Collagen deposition

2 (2–2)

2 (2–2)

p < 0.001

PCNA-positive nuclei

 Epidermis

2 (1–3)

2 (1–2)

p < 0.01

 Dermis

2 (2–3)

2(2–3)

BM-MSCs (n = 4)

Epithelial regeneration

1 (1–2)

1 (1–1)

p < 0.001

Inflammatory infiltrate

3 (2–3)

3 (3–3)

p = 0.99

Collagen deposition

1 (0–2)

1 (1–1)

p = 0.43

PCNA-positive nuclei

 Epidermis

1 (1–2)

2 (2–2)

p < 0.01

 Dermis

2 (2–3)

2 (2–2)

Control wounds (n = 27)

Epithelial regeneration

0 (0–1)

1 (0–1)

Inflammatory infiltrate

3 (3–3)

3 (2–3)

Collagen deposition

0 (0–1)

1 (1–2)

PCNA-positive nuclei

 Epidermis

0 (0–1)

3 (2–3)

 Dermis

0 (0–1)

3 (3–3)