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Table 1 Semi-quantitative scale for the histological parameters

From: Mesenchymal stromal cells for cutaneous wound healing in a rabbit model: pre-clinical study applicable in the pediatric surgical setting

Score

0

1

2

3

Re-epithelization rate

Early signs of re-epithelization

Regenerated mono-layered epithelium

Regenerated multi-layered epithelium

Differentiated multi-layered epithelium (stratum corneum)

Inflammatory infiltrate (white cells)

None

Few

Fair

Rich

Collagen content in granulation tissue

None

Poor

Moderate

High

PCNA in epidermis and dermis (positive nuclei/mm of epidermis or mm2 of dermis)

0

1–9

10–30

>30