Figure 6
Effect of febuxostat treatment on the expression of proteins regulating mitochondria-mediated apoptosis. a Representative Western blots from each group. b The levels of Cyto-C (cyto/mito).c The levels of cleaved caspase-3. d The levels of cleaved caspase-9. e The ratio of Bcl-2/Bax. f The levels of Bcl-2 and Bcl-XL. g The levels of Bax and Bak. Levels of proteins were quantified using densitometry and normalized against COX IV or GADPH. Data are presented as mean ± SD. **P < 0.01 vs. Con, ## P < 0.01 vs. H/R. These experiments were performed in quintuplicate with similar results.