Circulating resistin levels are early and significantly increased in deceased brain dead organ donors, correlate with inflammatory cytokine response and remain unaffected by steroid treatment

Table 2 Resistin level at the diagnosis of brain death is associated with cytokines at the diagnosis of brain death (T1) and at organ procurement (T2)

Cytokine	T1 all donors (n = 36)		T2 all donors (n = 36)		T2 untreated donors (n = 12)
Cytokine	r_s	P value	r_s	P value	r_s	p value
IFN-gamma	0.034	0.847	0.207	0.234	0.500	0.117
IL-1 beta	0.431	0.010	0.468	0.007	0.673	0.023
IL-2	0.350	0.046	0.248	0.178	0.700	0.016
IL-4	0.129	0.505	0.318	0.114	0.667	0.049
IL-6	0.398	0.018	0.511	0.002	0.727	0.011
IL-8	0.314	0.066	0.116	0.509	0.082	0.81
IL-10	0.217	0.210	0.372	0.028	0.318	0.340
IL-12	0.444	0.009	0.398	0.024	0.697	0.025
IL-13	0.503	0.003	0.397	0.030	0.482	0.133
TNF	0.249	0.149	0.427	0.011	0.455	0.160

The associations were assessed with two-tailed Spearman’s rank correlation test and the correlation coefficient (r_s) and p value are shown.

ISSN: 1479-5876