Figure 3

Personalized dysfunctional gene networks based on differential module related to prostate cancer. This module has its significant enrichment on KEGG prostate cancer pathway. It includes four DEGs as PDGFRB, PDGFB, SNX2, EGFR, and seven gene-pairs of DECGs as (PDGFRA, PDGFRB), (SNX4, PDGFRB), (PDGFB, PDGFRA), (SNX2, PDGFRA), (PDGFRB, PIK3R2), (EGFR, PIK3R2), (EGFR, AREG). The personalized network structures of this module have been displayed on five normal samples and other 15 disease samples, in which nodes with red/green colour represent genes with significantly high/low expression level, and edges with red/green colour represent gene-pairs with significantly high/low co-expression level.