Natural killer (NK) cell profiles in blood and tumour in women with large and locally advanced breast cancer (LLABC) and their contribution to a pathological complete response (PCR) in the tumour following neoadjuvant chemotherapy (NAC): differential restoration of blood profiles by NAC and surgery

Table 1 Presence of natural killer (NK) cells in the circulation (%, AbN) in women with LLABCs and HFDs

Cell phenotypes	In the circulation of women with LLABCs (n = 25)	In the circulation of HFDs (n = 10)	P value
NK (CD3⁻CD16⁺CD56^dim) (%)	8.50 ± 4.00	6.00 ± 1.75	0.805
NK (CD3⁻CD56^dim) (AbN:cells/µl)	160.0 ± 40.00	266.78 ± 55.00	0.020*

LLABCs large (≥3 cm) and locally advanced breast cancers (T3–4 N1–2 M0), HFDs healthy female donors.
* Values significantly reduced.

ISSN: 1479-5876