Bisphenol-A plasma levels are related to inflammatory markers, visceral obesity and insulin-resistance: a cross-sectional study on adult male population

Table 2 Clinical and biochemical parameters of the study population according to waist circumference

Parameters	WC ≤ 102 cm (n. 52)	WC > 102 cm (n. 24)	p values
Age (years)	53.6 ± 6.0	53.4 ± 5.2	0.900
BMI (kg/m²)	24.0 ± 2.5	29.1 ± 2.5	<0.0001
SBP (mmHg)	122.5 (90–160)	120.0 (100–160)	0.819
DBP (mmHg)	80.0 (65–95)	80.0 (60–100)	0.305
FPG (mg/dl)	101.4 ± 12	99.9 ± 11.7	0.613
Insulin (mU/l)	3.6 (1.2–26.4)	10.4 (3.3–28.7)	0.0006
HoMA-IR	0.9 (0.4–7.7)	2.7 (0.7–8.4)	0.0016
Total cholesterol (mg/dl)	212.0 ± 50.1	199.5 ± 35.2	0.273
HDL (mg/dl)	52.7 ± 11.8	43.6 ± 9.1	0.001
LDL (mg/dl)	132.9 ± 46.5	123.0 ± 30.2	0.344
TG (mg/dl)	149.8 ± 81.5	165.0 ± 53.4	0.407
BPA (ng/ml)	0.86 ± 0.72	1.44 ± 0.74	0.002
IL-6 (pg/ml)	0.77 (0.06–2.2)	0.78 (0.07–3.43)	0.030
MCP-1 (pg/ml)	26.9 ± 25.4	28.3 ± 19.3	0.808
TNFα (pg/ml)	1.1 (0.5–9.1)	3.2 (0.6–8.3)	0.007

Data are expressed as mean ± standard deviation or median, according to variable distribution. In particular, SBP, DBP, Insulin, HoMA-IR, IL-6 and TNFα were expressed as median with range. Differences in variables between groups were analyzed using the unpaired Student t test or Mann-Whitney U test, when appropriate.
BMI body mass index, WC waist circumference, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, HoMA-IR homeostasis model of assessment-insulin resistance, HDL high-density lipoprotein, LDL low-density lipoprotein, TG triglycerides, BPA bisphenol-A, IL-6 interleukin-6, MCP-1 monocyte chemoattractant protein-1, TNFα tumor necrosis factor-alpha.

ISSN: 1479-5876