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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Identification and selective expansion of functionally superior T cells expressing chimeric antigen receptors

Fig. 2

Antigen-stimulated CAR-T cells undergo selective expansion of the CARhi compartment. CFSE-labeled, CD8+ CAR-expressing cells or mock-transduced (CAR) T cells were co-incubated with parental (CD19) or CD19+ K562 targets without exogenous cytokines and monitored for a total T-cell count (left red axis) and CARhi or CARlo as a fraction of total CAR-T cells (right black axis), b median CFSE intensity, and c Annexin V staining. Average values of triplicates are shown with error bars indicating ± 1 standard deviation (s.d.)

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