Fig. 1

The schedule for autologous cellular immunotherapy (CIT). Autologous peripheral blood mononuclear cells (PBMCs) were collected by apheresis on D0, and were induced into NK, γδT, or CIK cells. The expanded immunocytes were then infused back into patients 14 days later (D14) as the initial transfusion. There were for 6 consecutive transfusion days (D14–D20) with 2 kinds of immune cells for each infusion, and each CIT course was completed within 3 weeks of apheresis. The second course of PBMCs collection was started 1 to 3 weeks after the end of the first course