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Table 1 Characteristics of all subjects included in the study

From: Development of a novel IGRA assay to test T cell responsiveness to HBV antigens in whole blood of chronic Hepatitis B patients

Characteristic

    
 

HCb

AHBb

CHBb, NUC treatment naive

CHBb, NUC treated

n

 

80

8

40

32

 

Male

69 (86.3 %)

4 (50 %)

20 (50 %)

23 (71.9 %)

 

Female

11 (13.8 %)

4 (50 %)

20 (50 %)

9 (28.1 %)

Age (yr)a

 

40.6 ± 12.0

45.9 ± 15

43.4 ± 14.9

47.3 ± 11.4

 

Male

40.2 ± 12.1

49.7 ± 11.8

41.2 ± 11.6

50.1 ± 11.2

 

Female

43.7 ± 11.5

42.2 ± 18.7

45.7 ± 17.6

40.0 ± 8.6

ALT (U/l)a

 

n.d.c

1046.0 ± 1035.0

37.7 ± 60.2

42.9 ± 39.3

AST (U/l)a

 

n.d.c

610.6 ± 702.5

26.6 ± 27.9

29.5 ± 27.7

HBV-DNA (IU/ml)a

 

n.d.c

2.88*106 ± 7.7*106

4.2*107 ± 1.8*108

1.6*107 ± 8.8*107

HBsAg (IU/ml)a

 

n.d.c

9153.4 ± 10,378.9

12,588.6 ± 20,958.8

4783.1 ± 6326.3

HBeAg

Negative

n.d.c

4 (50 %)

34 (85 %)

24 (77.4 %)

 

Positive

n.d.c

4 (50 %)

6 (15 %)

7 (22.6 %)

Anti-HBs

Negative

41 (51.2 %)

8 (100 %)

36 (90 %)

32 (100 %)

 

Positive

33 (41.3 %)

0 (0 %)

4 (10 %)

0 (0 %)

  1. aThe data are shown as means ± standard deviations
  2. bHC = healthy controls, AHB = acute hepatitis B, CHB = chronic hepatitis B
  3. cn.d. = not determined
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Journal of Translational Medicine

ISSN: 1479-5876

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