Table 3 Grade 3 and 4 toxicities

Leukopenia

65

Granulocytopenia

56

Anemia

27

Thrombocytopenia

21

Febrile neutropenia

27

Asthenia

27

Mucositis

14

Vomiting/Nausea

14

Diarrhea

2

Alopecia

2

Neurotoxicity

2

Anorexia

0

Venous thrombosis

12

Pulmonary embolism

8

Heart failure

2