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Table 1 Patient- and tumor characteristics

From: Statin-induced anti-proliferative effects via cyclin D1 and p27 in a window-of-opportunity breast cancer trial

Patients completed all study parts

n = 42

Age years (mean, range)

63 (35–89)

Tumor size mm (mean, range)

21 (6–33)

Positive nodal status

17 (41%)

Tumor grade (NHG)

 

 I

9 (21%)

 II

17 (41%)

 III

16 (38%)

Mitotic index

 

 1

23 (55%)

 2

5 (12%)

 3

14 (33%)

ER (n = 30)

 

 Positive

27 (90%)

 Negative

3 (10%)

PR (n = 30)

 

 Positive

24(80%)

 Negative

6 (20%)

HER2 (n = 29)

 

 0

7 (24%)

 1+

10 (34%)

 2+

7 (24%)

 3+

5 (17%)

Ki67 index (n = 26)

 

 Low

15 (58%)

 High

11 (42%)

HMGCR (n = 38)

 

 Positive

24 (63%)

 Negative

14 (37%)

  1. NHG Nottingham histologic grade I-III (post-treatment pathological report), Mitotic index according to Nottingham criteria (post-treatment pathological report).
  2. Baseline tumor data (pre-treatment): ER (estrogen receptor), PR (progesterone receptor), HER2 (human epidermal growth factor receptor 2), Ki67 high if >20%, HMGCR positive if any cytoplasmic staining.