Comparison of maraviroc, AMD3100 and ND-4043 on inhibition of HIV-1 replication (left panel X4, right panel R5). The antigen p24, expressed as ng/ml, is measured at day 7 post infection and data are reported as mean ± SD of three replicates. Infections were carried out in complete medium plus 10% of heat-inactivated FCS. Control PBMC were incubated with DMSO at 0.2% corresponding to the concentration present in 30 μM of ND-4043. The tested concentrations of compounds (ten fold dilutions) are shown in the figure.