Figure 5
Effect of ROS on migration and invasion of U251 glioma cells under hypoxia. (A) Intracellular production of ROS were measured by flow cytometry analysis. The ROS inhibitor apocynin reduced the expression of αvβ3 integrin (B), the phosphorylation of FAK and Pyk2 (C), as well as the migration and invasion (D) of U251 glioma cells under hypoxia. *p <0.05, **p <0.01 vs control.