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Table 3 Univariate and multivariate Cox regression models for each inflammatory prognostic variable

From: The prognostic role of systemic inflammatory markers on HIV-infected patients with non-Hodgkin lymphoma, a multicenter cohort study

Variables Category $    Univariate model   Multivariate model
n (%) # n HR (95% CI) P value n HR (95% CI) π P value
GPS* 0 20 (25.3) 79 Ref   65 Ref  
1 42 (53.2)   1.82 (0.49-6.69) NS   1.91 (0.45-7.65) NS
  2 17 (21.5)   4.39 (1.19-16.2) 0.026   4.78 (1.15-19.77) 0.031
  Available 79 (36.7)       
mGPS* 0 24 (30.4) 79 Ref   65 Ref  
  1 38 (48.1)   2.01 (0.61-7.00) NS   2.07 (0.61-7.01) NS
  2 17 (21.5)   4.46 (1.36-14.6) 0.013   4.35 (1.16-16.36) 0.029
  Available 79 (36.7)       
NLR 0 129 (67.2) 192 Ref     
  1 32 (16.7)   1.31 (0.74-2.30) NS    
  2 31 (16.1)   1.48 (0.84-2.61) NS    
  Mean (SD) 2.92 (2.79)       
  Available 192 (89.3)       
PLR 0 97 (48.3) 199 Ref     
  1 67 (33.3)   1.16 (0.71-1.90) NS    
  2 37 (18.4)   1.58 (0.88-2.84) NS    
  Mean (SD) 193.7 (135.1)       
  Available 199 (92.6)       
PI* 0 29 (31.9) 91 Ref   77 Ref  
  1 60 (65.9)   3.33 (1.12-9.93) 0.030   3.25 (1.06-9.94) 0.039
  2 2 (2.2)   3.98 (0.86-28.35) NS   11.3 (1.03-124.9) 0.047
  Available 91 (42.3)       
PNI* 0 54 (39.7) 136 Ref   114 Ref  
  1 82 (60.3)   2.36 (1.23-4.53) 0.010   2.57 (1.25-5.30) 0.010
  Available 136 (63.3)       
  1. Abbreviations: HR Hazard Ratio, 95% CI, 95% Confidence Interval, SD Standard Deviation, GPS Glasgow Prognostic Score, mGPS modified Glasgow Prognostic Score, NLR Neutrophil/Lymphocyte Ratio, PLR Platelet/Lymphocyte Ratio, PI Prognostic Index, PNI Prognostic Nutritional Index, NS Not Statistical Significant (p > 0.05).
  2. #Colum percentage, *Weighted Cox regression models, πModel adjusted for gender, age at diagnosis, intravenous drug user, AIDS defining event, CD4 cell count and HIV-RNA undetectable. $For prognostic variables classification see Table 1.