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Table 1 AQPs expression in different human tumors

From: Aquaporins as diagnostic and therapeutic targets in cancer: How far we are?

Aquaporins Tumor type Correlated function
AQP1 Brain cancer [13], Breast cancer [35], Colorectal cancer [34], Cervical cancer, Laryngeal cancer, Lung cancer [43], Nasopharyngeal cancer, Ovarian cancer [37] Tumor grade, prognosis, tumor angiogenesis, tumor necrosis, tumor cell migration, tumor invasion and metastasis.
AQP3 Colorectal cancer [34], Cervical cancer, Liver cancer [40], Lung cancer [9], Oesophageal cancer [39], Renal cancer [41], Skin cancer [38], Stomach cancer, Tongue cancer [42] Tumor grade, prognosis, tumor angiogenesis, tumor invasion, tumor cell migration and tumor energy metabolism.
AQP4 Brain cancer [14], Lung cancer [43], Thyroid cancer [44] Tumor grade, migration, tumor-associated edema, adhesion, invasion and tumor apoptosis.
AQP5 Breast cancer [9], Colorectal cancer [34,45], Cervical cancer, Leukaemia [46], Liver cancer [40], Lung cancer [47], Oesophageal cancer [39], Ovarian cancer [48], Stomach cancer [49], Tongue cancer [42] Tumor prognosis, tumor proliferation, tumor invasion, tumor cell migration and drug resistance.
AQP7 Thyroid cancer [50] Unknown
AQP8 Cervical cancer Tumor cell migration, tumor invasion, tumor metastasis and anti-apoptosis.
AQP9 Brain cancer [51], Ovarian cancer [52] Tumor grade, drug resistance and energy metabolism.