| |
NDCM (n = 8)
|
D (n = 8)
|
DR (n = 8)
|
DCM (n = 8)
|
DRCM (n = 8)
|
|---|
|
Serum creatinine (mg/dl)
|
0.56 ± 0.05#
|
0.36 ± 0.03
|
0.38 ± 0.03
|
0.89 ± 0.06*
|
0.42 ± 0.04+
|
|
Serum BUN (mg/dl)
|
14.98 ± 1.62
|
15.23 ± 1.32
|
16.26 ± 1.48
|
16.38 ± 1.93
|
16.45 ± 1.53
|
|
Creatinine clearance (ml/min)
|
1.53 ± 0.18#
|
2.68 ± 0.25
|
2.59 ± 0.24
|
1.08 ± 0.09*
|
1.98 ± 0.22+
|
|
FENa (%)
|
0.32 ± 0.15
|
0.29 ± 0.10
|
0.28 ± 0.09
|
0.31 ± 0.14
|
0.33 ± 0.13
|
|
Urine microprotein (mg/dl)
|
70.2 ± 22.1#
|
45.2 ± 11.3
|
38.6 ± 14.3
|
108.5 ± 23.4*
|
69.3 ± 18.2#
|
- NDCM: non-diabetic rats + contrast media, D: diabetic group, DCM: diabetic rats treat + contrast media, DR: diabetic rats + rosuvastatin, DRCM: diabetic rats + rosuvastatin + contrast media.
- *P < 0.01 vs NDCM, D, D R and DRCM; + P < 0.05 vs NDCM, D and DR, # P < 0.05 vs D, DR.
