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Table 1 Renal functional parameters in the study groups (mean ± SD)

From: Rosuvastatin attenuates contrast-induced nephropathy through modulation of nitric oxide, inflammatory responses, oxidative stress and apoptosis in diabetic male rats

  NDCM (n = 8) D (n = 8) DR (n = 8) DCM (n = 8) DRCM (n = 8)
Serum creatinine (mg/dl) 0.56 ± 0.05# 0.36 ± 0.03 0.38 ± 0.03 0.89 ± 0.06* 0.42 ± 0.04+
Serum BUN (mg/dl) 14.98 ± 1.62 15.23 ± 1.32 16.26 ± 1.48 16.38 ± 1.93 16.45 ± 1.53
Creatinine clearance (ml/min) 1.53 ± 0.18# 2.68 ± 0.25 2.59 ± 0.24 1.08 ± 0.09* 1.98 ± 0.22+
FENa (%) 0.32 ± 0.15 0.29 ± 0.10 0.28 ± 0.09 0.31 ± 0.14 0.33 ± 0.13
Urine microprotein (mg/dl) 70.2 ± 22.1# 45.2 ± 11.3 38.6 ± 14.3 108.5 ± 23.4* 69.3 ± 18.2#
  1. NDCM: non-diabetic rats + contrast media, D: diabetic group, DCM: diabetic rats treat + contrast media, DR: diabetic rats + rosuvastatin, DRCM: diabetic rats + rosuvastatin + contrast media.
  2. *P < 0.01 vs NDCM, D, D R and DRCM; + P < 0.05 vs NDCM, D and DR, # P < 0.05 vs D, DR.