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Table 4 Prediction of variable in study for the risk of developing DR in T2DM patients by multiple regression analysis

From: Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population

Variables

T2DM patients without DR (DNR)

T2DM patients with DR

t-statistics value (t)

P value

N (%)

N (%)

Age (mean ± SD)

55.64 ± 10.23

57.86 ± 8.67

0.29

0.776

Gender (Males vs Females)

58 (36.3%)/102 (63.8%)

36 (46.2%)/42 (53.8%)

1.13

0.262

BMI (mean ± SD)

34.08 ± 6.99

33.92 ± 6.53

−0.463

0.644

Creatinine level (micromole/lit) ± SD

69.30 ± 28.55

81.5 ± 45.27

1.82

0.070

Glycated hemoglobin (HbA1c) mean% ± SD

8.24 ± 1.72

8.82 ± 1.83

1.99

0.048

LDL(mmol/lit)mean ± SD

2.95 ± 0.94

2.68 ± 1.04

−2.22

0.028

Triglycerides (mmol/lit) mean ± SD

1.77 ± 1.23

1.62 ± 0.75

−1.07

0.286

Blood Urea Nitrogen (mmol/lit) mean ± SD

5.24 ± 2.54

6.97 ± 4.49

−0.944

0.347

Mean Glucose levels (mmole/lit) ± SD

10.55 ± 6.68

9.92 ± 4.23

−0.165

0.87

SLMAP rs17058639 C > T genotypes

TT = 29 (18.1%)

TT = 6 (7.7%)

−2.15

0.033

CT = 71 (44.4%)

CT = 30 (38.5%)

CC = 60 (37.5%)

CC = 42 (53.8%)

SLMAP rs1043045 C > T

CC = 31 (19.4%)

CC = 9 (11.5%)

0.95

0.294

CT = 70 (43.8%)

CT = 31 (39.7%)

TT = 59 (36.9%)

TT = 38 (48.7%)

SLMAP rs1057719 A > G

GG = 30 (18.8%)

GG = 8 (10.3%)

0.10

0.319

AG = 71 (44.4%)

AG = 32 (41.0%)

AA = 59 (36.9%)

AA = 38 (48.7%)

  1. t= > +2 or < −2 depicts significance in data; significant values shown in bold.