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Table 3 The association between patients’ pathological data and inflammatory biomarkers

From: Prognostic value of pre-operative inflammatory response biomarkers in gastric cancer patients and the construction of a predictive model

Variables Tumor grade a P * Tumor stage b P * Depth of invasion P * Lymph node P * Distant metastasis P *
G1-G2 G3-G4 I-II III-IV T1-T2 T3-T4 N0 N1-N3 M0 M1
NLR 6.51 ± 10.79 5.64 ± 6.81 0.512 4.73 ± 6.73 7.07 ± 10.50 0.000 4.02 ± 6.67 6.54 ± 9.60 0.000 4.81 ± 8.03 6.41 ± 9.45 0.000 5.00 ± 7.92 7.82 ± 10.70 0.000
dNLR 4.08 ± 5.94 3.51 ± 3.61 0.516 3.13 ± 3.63 4.31 ± 5.76 0.000 2.67 ± 3.24 4.06 ± 5.29 0.000 3.01 ± 3.92 4.01 ± 5.23 0.000 3.32 ± 4.51 4.61 ± 5.65 0.013
PLR 210 ± 248 169 ± 103 0.185 170 ± 121 207 ± 235 0.010 146 ± 135 201 ± 206 0.039 160 ± 137 199 ± 208 0.001 170 ± 122 225 ± 272 0.001
LMR 4.65 ± 3.73 4.95 ± 5.83 0.808 5.74 ± 5.93 4.13 ± 3.66 0.001 6.90 ± 8.55 4.36 ± 3.42 0.000 6.71 ± 8.31 4.35 ± 3.40 0.000 5.70 ± 5.79 3.39 ± 1.88 0.000
  1. NLR, neutrophil count to lymphocyte count; dNLR, neutrophil count to (white cell count – neutrophil count); PLR, platelet count to lymphocyte count; LMR, lymphocyte to monocyte ratio
  2. *Difference between groups was tested by Mann–Whitney U or Kruskal-Wallis test.
  3. aGrade 1 and 2 stand for high or middle differentiated tumor, grade 3 and 4 stand for poorly differentiated tumor.
  4. bTumor stage according to seventh edition of American Joint of Committee on Cancer.