Figure 1
From: Interleukin-37 is increased in ankylosing spondylitis patients and associated with disease activity
Comparison of IL-37 mRNAs and protein levels between AS and HC. (A) The expressions of IL-37 mRNA from PBMCs in active (n = 25) and inactive AS patients (n = 21) and in HC (n = 35) were measured by RT-PCR, results are expressed as mean ± SEM. (B) Serum IL-37 levels in an active (n = 25) and inactive AS patients (n = 21) and HC (n = 35) were measured by ELISA. Each symbol represents an individual AS patient and HC. Horizontal lines indicate median values. Differences between two groups were performed with Mann–Whitney U-test for nonparametric data. AS, ankylosing spondylitis; HC, healthy control; NS, not significant; *P < 0.05; **P < 0.01.