Table 2 Significantly differentiated methylated CpG sites of newborns exposed to inutero tobacco compared to non-exposed
From: DNA methylation patterns in newborns exposed to tobacco in utero
CpG | Chromosome | Gene | Logfold change | p-value | Adjusted p-value | Delta beta | Rank | CpG_location |
|---|---|---|---|---|---|---|---|---|
cg05727225 | 11p15.4 | ADM | 0.3474 | 1.32xe-07 | 0.03282 | 0.0432 | 1 | CpG island |
cg00387170 | 6p21.1 | FOXP4 | 0.4894 | 2.71xe-07 | 0.03282 | 0.0740 | 2 | CpG island |
cg13907959 | 1q42.13 | HIST3H2A | −0.4731 | 2.72xe-07 | 0.03282 | −0.0409 | 3 | CpG island |
cg02738677 | 1q42.13 | HIST3H2A | 0.4894 | 5.56xe-07 | 0.0385 | 0.0685 | 4 | Non-CGI |
cg04402350 | 4q31.22 | ZNF827 | 0.5450 | 3.07xe-07 | 0.0328 | 0.0676 | 5 | CPG island |
cg25783241 | 21q22.3 | AIRE | 0.2620 | 6.34xe-07 | 0.0385 | 0.0435 | 6 | CPG island |
cg04177517 | 19q13.11 | GPATCH1 | 0.3278 | 8.06xe-07 | 0.0385 | 0.0778 | 7 | CGI-Shore |
cg12331332 | 10q25 | CASP7 | 0.3305 | 9.07xe-07 | 0.0385 | 0.0390 | 8 | CPG island |
cg24962978 | 11q23.3 | RPS25 | 0.5570 | 9.13xe-07 | 0.0385 | 0.0742 | 9 | CPG island |
cg15264752 | 6p21.3 | DDAH2 | 0.4845 | 1.00xe-06 | 0.0385 | 0.0526 | 10 | CPG island |
cg23240961 | 12q13.3 | NDUFA4L2 | 0.5615 | 1.06xe-06 | 0.0385 | 0.0666 | 11 | CPG island |
cg27561567 | 17q11-qter | CLTC | 0.2552 | 1.08xe-06 | 0.0385 | 0.0623 | 12 | Non-CGI |
cg08533403 | 19q13.2 | PLD3 | 0.4951 | 1.31xe-06 | 0.0403 | 0.0750 | 13 | CPG island |
cg03621881 | 15q24 | CELF6 | 0.4745 | 1.32xe-06 | 0.0403 | 0.0522 | 14 | CPG island |
cg12556991 | 17q21 | RPL27 | 0.5845 | 1.55xe-06 | 0.0403 | 0.0528 | 15 | CPG island |
cg13549152 | 1p34.3 | AKIRIN1 | 0.2472 | 1.57xe-06 | 0.0403 | 0.0494 | 16 | CGI-Shore |
cg10454248 | 13q14.3 | FAM124A | 0.5438 | 1.60xe-06 | 0.0403 | 0.0532 | 17 | CPG island |
cg09048334 | 17q21 | RPL27 | 0.3934 | 1.98xe-06 | 0.0472 | 0.0919 | 18 | CPG island |
cg00093900 | 1q32.1 | PPP1R15B | 0.3873 | 2.39xe-06 | 0.0494 | 0.0363 | 19 | CPG island |
cg02192300 | 13q14.3 | FAM124A | 0.3810 | 2.63xe-06 | 0.0494 | 0.0446 | 20 | CPG island |
cg03529555 | 11p15.1 | NAV2 | −0.4831 | 2.72xe-06 | 0.0494 | 0.0642 | 21 | Non-CGI |
cg26547359 | HS3ST5 | −0.4682 | 2.89xe-06 | 0.0494 | 0.0524 | 22 | CPG island | |
cg01249134 | 11p15.1 | NAV2 | 0.3364 | 3.05xe-06 | 0.0494 | 0.0758 | 23 | CGI-Shelf |
cg07455406 | RSU1 | 0.2540 | 3.08xe-06 | 0.0494 | 0.0624 | 24 | CPG island | |
cg12271800 | 19q13.43 | ZBTB45 | 0.4554 | 3.10xe-06 | 0.0494 | 0.0473 | 25 | CPG island |
cg25932748 | 2q24.1 | KCNJ3 | 0.5870 | 3.18xe-06 | 0.0494 | 0.0666 | 26 | CGI-Shore |
cg17423711 | 1q24.2 | POU2F1 | 0.3053 | 3.24xe-06 | 0.0494 | 0.0260 | 27 | CPG island |
cg23332582 | 3q23 | SPSB4 | 0.3668 | 3.36xe-06 | 0.0494 | 0.0673 | 28 | CPG island |
cg09352908 | 5q12 | PDE4D | 0.4439 | 3.38xe-06 | 0.0494 | 0.0637 | 29 | CGI-Shore |
cg22078451 | 5q12 | PDE4D | 0.5968 | 3.53xe-06 | 0.0494 | 0.0641 | 30 | CPG island |
cg20916068 | 0.4586 | 3.58xe-06 | 0.0494 | 0.0986 | 31 | Non-CGI |