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Figure 9 | Journal of Translational Medicine

Figure 9

From: Administered circulating microparticles derived from lung cancer patients markedly improved angiogenesis, blood flow and ischemic recovery in rat critical limb ischemia

Figure 9

Protein expressions of apoptotic and anti-apoptotic biomarkers in ischemic quadriceps on day 14 following critical limb ischemia (CLI) procedure (n =  8). A) Protein expression of mitochondrial Bax (mito-Bax) in four groups (SC = sham control; SC + Lc-MPs = sham control + lung-cancer patient-derived microparticles; CLI = critical limb ischemia; CLI + Lc-MPs = critical limb ischemia + lung-cancer patient-derived microparticles), * vs. other groups with different symbols (*, †, ‡), p < 0.001. B) The protein expression of cytosolic Bax (cyto-Bax) in four groups, * vs. other groups with different symbols (*, †, ‡), p < 0.001. C) Protein expression of cleaved caspase (c-Csp) 3 in four groups, * vs. other groups with different symbols (*, †, ‡), p < 0.001. D) Protein expression of cleaved poly (ADP-ribose) polymerase (PARP), * vs. other groups with different symbols (*, †, ‡), p < 0.001. E) The protein expression of Bcl-2, * vs. other groups with different symbols (*, †, ‡), p < 0.001.

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