Table 2 Frequencies of circulating immune subsets in melanoma patients
Cell type | Cell frequency (mean % - SD)* | Dichotomization cut-off (%)* | Patients with “high” cell levels (%) |
|---|---|---|---|
Dendritic cells (DC) | 1.54 (0.54) | ||
Plasmacytoid DCs | 0.34 (0.18) | 0.2515 | 66.7 |
Myeloid DCs | 0.96 (0.40) | ||
Myeloid-derived suppressor cells (MDSC) | 4.00 (2.29) | 4.13 | 33.3 |
Monocytic MDSC | 2.94 (2.81) | ||
Polymorphonuclear MDSC | 1.04 (0.64) | ||
CD3+ cells | 43.60 (9.32) | 40.25 | 68.2 |
Cytotoxic T-cell | 14.79 (6.06) | ||
Regulatory T-cell | 4.77 (1.35) | ||
CTLA-4 expression by Tregs | 92.32 (4.01) | 93.7 | 37.3 |