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Table 2 Effect of AA on serum biochemical parameters of T2D rats

From: Abroma augusta L. (Malvaceae) leaf extract attenuates diabetes induced nephropathy and cardiomyopathy via inhibition of oxidative stress and inflammatory response

Parameters Gr I Gr II Gr III Gr IV Gr V
Total cholesterol (mg dl−1) 87.12 ± 3.60 131.32 ± 3.73# 104.22 ± 5.02* 97.53 ± 3.70** 94.43 ± 3.67**
HDL-cholesterol (mg dl−1) 33.10 ± 2.94 18.14 ± 1.13# 24.61 ± 2.41 28.98 ± 3.60* 31.38 ± 3.17**
Triglycerides (mg dl−1) 76.27 ± 3.78 123.08 ± 6.13# 104.22 ± 5.67 96.40 ± 7.10* 82.62 ± 5.60**
Insulin (μg dl−1) 2.68 ± 0.18 1.64 ± 0.14# 2.02 ± 0.11 2.17 ± 0.10* 2.23 ± 0.14*
Glycosylated haemoglobin (mg g−1 haemoglobin) 0.27 ± 0.45 0.67 ± 0.62# 0.49 ± 0.73 0.42 ± 0.65* 0.39 ± 0.33**
ALT (IU l−1) 69.83 ± 4.16 101.43 ± 7.49# 84.55 ± 6.35 79.33 ± 5.13* 73.98 ± 6.13*
AST (IU l−1) 45.32 ± 4.09 71.69 ± 4.47# 58.91 ± 5.38 54.69 ± 6.81 51.20 ± 6.34*
Urea (mg dl−1) 30.63 ± 2.41 65.04 ± 4.99# 46.56 ± 3.88** 44.76 ± 3.07** 41.86 ± 3.52**
Lactate dehydrogenase (U l−1) 207.52 ± 9.36 294.04 ± 15.24# 253.75 ± 15.68 242.82 ± 13.10* 238.33 ± 9.98*
Creatinine kinase (IU mg−1 protein) 4.73 ± 0.38 8.21 ± 0.50# 6.54 ± 0.57 6.12 ± 0.39* 5.76 ± 0.45**
C-reactive protein (mg dl−1) 1.02 ± 0.10 3.24 ± 0.24# 2.18 ± 0.24* 2.09 ± 0.32** 1.61 ± 0.19**
  1. Data were expressed as mean ± SE (n = 6). # p < 0.01 compared with normal control group. *p < 0.05 compared with diabetic control group.
  2. **p < 0.01 compared with diabetic control group. Gr I: Normal; Gr I: Normal; Gr II: T2D control, Gr III: T2D + AA (100 mg/kg, p.o.); Gr IV: T2D + AA (200 mg/kg, p.o.); Gr V: T2D + glibenclamide (1 mg/kg, p.o.).