Figure 9

Expressions of angiogenesis and cardiac progenitor cell biomarkers in LV myocardium at 72 h after IR procedure. A) Protein expression of stromal cell-derived factor (SDF)-1α in LV myocardium. p < 0.01, * vs. other groups with different symbols (*, †, ‡). B) Protein expression of CXCR4 in LV myocardium. p < 0.01, * vs. other groups with different symbols (*, †, ‡). C) Expression of c-kit + cells in LV myocardium. <0.0001, * vs. other groups with different symbols (*, †, ‡, §). D) Expression of Sca-1+ cells in LV myocardium. <0.0001, * vs. other groups with different symbols (*, †, ‡, §). All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple comparison post hoc test (n = 8). Symbols (*, †, ‡) indicate significance (at 0.05 level). WT-SC = wide type sham control; WT-IR = wide type + ischemia reperfusion; DDP4^D-SC = dipeptidyl peptidase-IV (DPP4) deficiency sham control; DDP4^D-IR = DDP4^D + ischemia reperfusion; WT-IR-Sita = wide type + ischemia reperfusion + sitagliptin.