Figure 2
From: Response of recurrent BRAFV600E mutated ganglioglioma to Vemurafenib as single agent
Tumor histology at second biopsy. (A) At the second biopsy, the neoplasm showed the presence of clusters of mature ganglion cells (arrow) in the mist of bland astrocytic cells. (B) The ganglion cells showed strong immunoreactivity for synaptophysin (C). Electropherogram illustrate BRAF V600E (GTG/GAG) mutation detection (arrow) in tumor DNA derived from formalin-fixed paraffin-embedded specimens.