Figure 6
From: Overcoming tumor immune evasion with an unique arbovirus
H & E staining for Death Receptors DR4 and DR5, compared to Decoys DcR1 and DcR2. In primary epithelial cells (top row), staining of DR4/5 is greater then DcR1/2. In metastatic lesions, (bottom row), the relative expressions are reversed, conferring resistance to TRAIL-mediated apoptosis. With permission from Springer Images for non-commercial use [93].