ABE treatment enhances osteogenesis and reverses bone marrow adipogenesis. (A) Histological features of normal bone from a normal rat, and osteonecrotic bone from rats with steroid-induced ONFH with or without ABE treatment. (B) Statistical analysis of the differences of the ratio of empty lacuna, adipose tissue area, and adipocyte perimeter in the control, model, ABE 10 g/kg, ABE 15 g/kg, and ABE 22.5 g/kg groups. Data are presented as the mean ± S.D. (n =20 for control, n =25 for model group, n =20 for ABE treatment groups). ##: P <0.01, in comparison with the control group. * and **: P <0.05 and P <0.01, respectively, in comparison with the model group. The arrow heads indicate necrosis area.