Table 2 Clinical characteristics and cell-staining characteristics of patients whose CTCs were evaluated by ImageStreamX
Patient ID | Prior therapies* | PSA (ng/mL) | EpCAM + Events | CTCs (%) | Mean AR intensity#(STDev) | Median AR intensity#(Range) | AR-high CTCs (%) | Mean SI (STDev) | Median SI (Range) |
|---|---|---|---|---|---|---|---|---|---|
12077 | L, B | 168.4 | 5 | 4 (80) | 117262 (120651) | 89033 (29879-322996) | 5 (100) | 0.67 (1.67) | -0.09 (-0.43-3.55) |
12076 | L, B, K, A | 41.16 | 115 | 114 (99) | 337937 (286897) | 253104 (-6509-1427349) | 108 (94) | -0.12 (0.85) | -0.25 (-1.79-2.31) |
12079 | L, B, S | 32.24 | 104 | 96 (92) | 25456 (36815) | 11486 (1096-193627) | 63 (61) | 0.72 (1.06) | 0.57 (-0.78-4.27) |
12078 | L, B, K | 11.12 | 33 | 27 (82) | 3202 (12736) | 216 (-9849-56081) | 5 (15) | 0.97 (1.21) | 0.95 (-0.98-2.06) |
12080 | L, B, D, C, A, E | 554 | 0 | NA | NA | NA | NA | NA | NA |
12081 | L, D, C | 275.4 | 36 | 24 (67) | 33078 (58419) | 4115 (-12080-240098) | 16 (44) | -0.05 (1.51) | -0.44 (-1.77-3.79) |
12082 | B, S | 5.78 | 18 | 11 (61) | 59487 (213913) | 1437 (-6856-913784) | 6 (33) | 0.39 (0.94) | 0.21 (-0.62-1.64) |
12083 | L, B, A, E | 522.3 | 12 | 11 (92) | 38260 (29857) | 30748 (3725-92097) | 9 (75) | 0.3 (1.11) | -0.21 (-0.98-2.39) |
12084 | L | 164.1 | 24 | 16 (67) | 78782 (214426) | 795 (-5122-800180) | 8 (33) | 0.6 (1.6) | 0.17 (-1.02-3.63) |
12081 | L, D, C | 382.6 | 15 | 5 (33) | -2323 (4049) | -2592 (-10466-4384) | 0 | NA | NA |
12079 | L, B, S | 39.3 | 0 | NA | NA | NA | NA | NA | NA |
12086 | B, L, K, D, A, E, Sa | 1152 | 121 | 116 (96) | 5674 (17971) | 4256 (-13238-182505) | 13 (11) | 0.39 (0.66) | 0.6 (-0.93-1.13) |
12087 | L, B | 20.35 | 35 | 35 (100) | -11351 (21968) | -7673 (-68443-33422) | 4 (11) | -0.46 (0.63) | -0.31 (-1.33-0.12) |
12086 | B, L, K, D, A, E, Sa | 1320 | 11 | 11 (100) | 115581 (88954) | 102918 (46540-360131) | 11 (100) | -0.36 (0.44) | -0.45 (-0.9-0.64) |
12088 | L, B, D | 0.06 | 21 | 18 (86) | 254074 (980505) | 3184 (-1368-4502881) | 4 (19) | -0.2 (2.65) | 0.99 (-4.17-1.38) |
12028-101 | L, B, D, A, E | 37.23 | 50 | 48 (96) | 241547 (1561372) | 4910 (-3059-11054469) | 12 (24) | 0.58 (1.51) | 0.35 (-1.88-3.73) |
12064-102 | L, B, K, A, C | 6.33 | 4 | 3 (75) | 55055 (63046) | 44257 (1328-130379) | 2 (50) | 3.74 (0.35) | 3.74 (3.49-3.99) |
12072-103 | B, L, A, D | 20.59 | 220 | 215 (98) | 21851 (48606) | 7965 (-45736-465037) | 92 (42) | -0.1 (0.64) | -0.17 (-1.2-2.06) |
12080-104 | L, B, D, C, A, E | 1040 | 3 | 2 (67) | 81694 (72851) | 108774 (-819-137127) | 2 (67) | 2.36 (0.43) | 2.36 (2.06-2.67) |
14093 | Ci/Et, To, Et/Te | 1.83 | 7 | 6 (86) | 5566 (12133) | 2578 (-8042-29243) | 2 (29) | -0.12 (0.36) | -0.12 (-0.38-0.13) |
12027-105 | L, B, N, K, D/Da, A, E, R | 489.8 | 40 | 40 (100) | 7995 (31246) | 3127 (-62338-124132) | 5 (13) | 1.32 (0.87) | 1.65 (0.3-2.34) |
14093 | Ci/Et, To, Et/Te | 1.98 | 23 | 22 (96) | 500281 (2345906) | 3774 (-9141-11261273) | 8 (35) | -0.33 (1.54) | 0.06 (-3.94-1.17) |
12064-102 | L, B, K, A, C | 6.84 | 411 | 408 (99) | 11281 (21967) | 7020 (-6031-267789) | 115 (28) | 0.74 (0.52) | 0.8 (-0.75-1.82) |
12072-103 | B, L, A, D | 25.8 | 30 | 30 (100) | 12437 (37826) | 4871 (-19268-203291) | 8 (27) | 0.34 (0.68) | 0.19 (-0.29-1.78) |
12088 | L, B, D | 0.06 | 100 | 99 (99) | 5505 (15912) | 1670 (-13453-118622) | 13 (13) | 0.01 (0.61) | -0.17 (-0.89-1.3) |
14092 | L, B, K, N, A, R | 498.7 | 13 | 11 (85) | 51770 (97952) | 689 (-60783-230484) | 5 (38) | 1.86 (0.82) | 2.03 (0.48-2.6) |
12028-101 | L, B, D, A, E | 46.31 | 29 | 27 (93) | 23411 (69628) | 4050 (-5317-359215) | 7 (24) | 0.92 (1.22) | 0.37 (-0.62-2.85) |
12076-106 | L, B, K, A, D | 9.33 | 59 | 59 (100) | 29569 (74779) | 9686 (-24144-356079) | 29 (49) | 1.09 (0.65) | 1.05 (-0.11-3.43) |
14090 | L, B, N, S, A | 6.81 | 10 | 8 (80) | 41168 (90507) | -4692 (-83596-201844) | 4 (40) | 2.38 (0.52) | 2.38 (1.76-3.02) |
14089 | L, B | 5.06 | 11 | 9 (82) | 192342 (687361) | -2246 (-149355-2254943) | 3 (27) | 2.33 (1.29) | 1.71 (1.47-3.82) |
14089 | L, B | 5.87 | 8 | 2 (25) | 1953000 (5025861) | 218121 (-25632-14383254) | 6 (75) | 1.02 (1.71) | 1.53 (-2.35-2.49) |