Table 2 Univariate analysis of prognostic factors

Gender

0.504

 Male

61

47

16.176

1

 Female

47

37

19.699

0.862 (0.559-1.331)

Age (y)

0.176

 < 60

47

35

21.381

1

 ≥ 60

61

49

15.254

1.352 (0.874-2.092)

Location of tumor

0.026^*

 Head

72

52

20.770

1

 Body and tail

36

32

12.235

1.655 (1.062-2.579)

Size of tumor (cm)

0.358

 ≤ 2

22

67

20.116

1

 >2

86

17

17.290

1.285 (0.753-2.192)

Differentiation

<0.001^*

 Well

15

8

34.953

1

 Moderate

83

66

15.803

2.532 (1.202-5.332)

0.015^*

 Poor

10

10

5.700

7.624 (2.918-19.916)

<0.001^*

Nerve infiltration

0.699

 No

38

29

21.137

1

 Yes

70

55

16.406

1.094 (0.694-1.725)

TNM staging

0.007^*

 IA + IB

15

12

24.448

1

 IIA

33

25

17.483

1.371 (0.684-2.751)

0.374

 IIB

46

34

18.785

1.507 (0.777-2.925)

0.225

 III + IV

14

13

6.982

3.729 (1.664-8.358))

0.001^*

Serum CA19-9 (kU/L)

0.014^*

 ≤ 39

31

16

28.993

1

 > 39

77

68

14.556

1.988 (1.150-3.436)

Serum CA50 (kU/L)

0.065^*

 ≤ 25

49

30

24.091

1

 > 25

59

54

14.459

1.529 (0.975-2.398)

Serum CEA (μg/L)

0.032^*

 ≤ 5

64

44

22.116

1

 > 5

44

40

12.072

1.609 (1.041-2.488)

MUC4 (2^-ΔCt)

<0.001^*

 Low (<0.056)

75

54

22.101

1

 High (≥0.056)

33

30

8.054

2.595 (1.612-4.179)

MUC4/Y (2^-ΔCt)

0.003^*

 Low (<0.0044)

79

58

21.126

1

 High (≥0.0044)

29

26

8.835

2.077 (1.283-3.365)