|
Measurement
|
Arm
|
Baseline
|
3 month
|
6 month
|
|---|
|
HR (beats/min)
|
Control
|
103 ± 6
|
135 ± 9
|
139 ± 11
|
| |
VNS
|
106 ± 6
|
137 ± 10
|
122 ± 7*
|
|
mAoP (mm Hg)
|
Control
|
99 ± 5
|
85 ± 8
|
80 ± 8
|
| |
VNS
|
97 ± 5
|
86 ± 9
|
78 ± 9
|
|
PCWP (mm Hg)
|
Control
|
5.9 ± 0.4
|
17.4 ± 1.4
|
19.1 ± 1.9
|
| |
VNS
|
5.7 ± 0.5
|
18.6 ± 1.6
|
13.2 ± 1.7*
|
|
dp/dtmax (mm Hg/s)
|
Control
|
2543 ± 226
|
1925 ± 255
|
1782 ± 278
|
| |
VNS
|
2496 ± 209
|
1911 ± 243
|
1938 ± 295
|
|
RF (%)
|
Control
|
58 ± 3
|
63 ± 4
|
61 ± 5
|
| |
VNS
|
59 ± 3
|
65 ± 4
|
61 ± 6
|
|
LVEDD (cm)
|
Control
|
3.5 ± 0.2
|
4.9 ± 0.3
|
5.8 ± 0.3
|
| |
VNS
|
3.4 ± 0.2
|
4.8 ± 0.3
|
6.1 ± 0.4
|
|
LVESD (cm)
|
Control
|
1.9 ± 0.1
|
2.6 ± 0.1
|
3.1 ± 0.3
|
| |
VNS
|
1.8 ± 0.1
|
2.5 ± 0.1
|
3.2 ± 0.3
|
|
LVEDV (ml)
|
Control
|
43 ± 4
|
84 ± 10
|
110 ± 12
|
| |
VNS
|
42 ± 4
|
85 ± 10
|
117 ± 13
|
|
LVESV (ml)
|
Control
|
19 ± 3
|
30 ± 8
|
41 ± 10
|
| |
VNS
|
18 ± 3
|
28 ± 8
|
42 ± 11
|
|
LV mass/BW (g/kg)
|
Control
|
3.8 ± 0.2
|
5.5 ± 0.3
|
5.8 ± 0.3
|
| |
VNS
|
3.7 ± 0.2
|
5.4 ± 0.3
|
6.3 ± 0.3*
|
- Values presented as mean ± SEM. *P < 0.05 compared with the control.
- HR = heart rate; mAoP = mean aortic pressure; PWCP = Pulmonary capillary wedge pressure; RF = regurgitant fraction; LV = left ventricle/ventricular; EDD = end-diastolic dimension; EDV = end- diastolic volume; ESD = end-systolic dimension; ESV = end-systolic volume; BW = body weight.
