Table 1 Left ventricular function and hemodynamics in MR: effect of VNS

HR (beats/min)

Control

103 ± 6

135 ± 9

139 ± 11

VNS

106 ± 6

137 ± 10

122 ± 7*

mAoP (mm Hg)

Control

99 ± 5

85 ± 8

80 ± 8

VNS

97 ± 5

86 ± 9

78 ± 9

PCWP (mm Hg)

Control

5.9 ± 0.4

17.4 ± 1.4

19.1 ± 1.9

VNS

5.7 ± 0.5

18.6 ± 1.6

13.2 ± 1.7*

dp/dt_max (mm Hg/s)

Control

2543 ± 226

1925 ± 255

1782 ± 278

VNS

2496 ± 209

1911 ± 243

1938 ± 295

RF (%)

Control

58 ± 3

63 ± 4

61 ± 5

VNS

59 ± 3

65 ± 4

61 ± 6

LVEDD (cm)

Control

3.5 ± 0.2

4.9 ± 0.3

5.8 ± 0.3

VNS

3.4 ± 0.2

4.8 ± 0.3

6.1 ± 0.4

LVESD (cm)

Control

1.9 ± 0.1

2.6 ± 0.1

3.1 ± 0.3

VNS

1.8 ± 0.1

2.5 ± 0.1

3.2 ± 0.3

LVEDV (ml)

Control

43 ± 4

84 ± 10

110 ± 12

VNS

42 ± 4

85 ± 10

117 ± 13

LVESV (ml)

Control

19 ± 3

30 ± 8

41 ± 10

VNS

18 ± 3

28 ± 8

42 ± 11

LV mass/BW (g/kg)

Control

3.8 ± 0.2

5.5 ± 0.3

5.8 ± 0.3

VNS

3.7 ± 0.2

5.4 ± 0.3

6.3 ± 0.3*