Figure 3
Essential genes in the metabolism of Mtb required for its growth and survival. A) Protein concentration of single gene knock-out lethal genes, (B) enzymatically low efficient genes and (C) metabolically low efficient genes with respect to mean abundance of complete Mtb proteome. Literature based qualitative assessment of (D) single gene knock-out essential genes, (E) enzymatically low efficient genes, (F) metabolically low efficient genes and (G) genes belonging to all the structural modules respectively (H) transcriptional control of genes mapped to various reaction topological modules on reaction-reaction graph of Mtb metabolism.