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Table 1 Correlation between LOC285194 expression and clinicopathologic characteristics of 142 ESCC patients

From: Association of decreased expression of long non-coding RNA LOC285194 with chemoradiotherapy resistance and poor prognosis in esophageal squamous cell carcinoma

Variables

LncRNA LOC285194 subgroupa

P bvalue

Low

High

All cases

71

71

 

Gender

   

Male

49 (69.1%)

45 (63.3%)

0.478

Female

22 (30.0%)

26 (36.7%)

 

Age (years)

  

0.614

≤55

8 (11.3%)

10 (14.1%)

 

>55

63 (88.7%)

61 (85.9%)

 

Tumor size (cm)

  

0.002*

≤5

39 (55.0%)

57 (80.3%)

 

>5

32 (45.0%)

14 (19.7%)

 

Tumor location

  

0.573

Cervical/upper thoracic

6 (8.5%)

8 (11.3%)

 

Middle/lower thoracic

65 (91.5%)

63 (88.7)

 

Histologic grade

  

0.022*

G1

6 (8.5%)

7 (9.9%)

 

G2

36 (50.7%)

50 (70.4%)

 

G3/G4

29 (40.8%)

14 (19.7%)

 

Smoking status

  

0.603

Ever/current

28 (39.4%)

25 (35.2%)

 

Never

43 (60.6%)

46 (64.8%)

 

Alcohol consumption

  

0.206

Ever/current

17 (23.9%)

11 (15.5%)

 

Never

54 (76.1%)

60 (84.5%)

 

T status

  

0.27

T1/2

18 (25.4%)

24 (33.8%)

 

T3/4

53 (74.6%)

47 (66.2%)

 

N status

  

0.013*

N0M0

23 (32.4%)

39 (54.9%)

 

N1M0

22 (31.0%)

19 (26.8%)

 

M1-lymc

26 (36.6%)

13 (18.3%)

 

M status

  

0.015*

M0

45 (63.4%)

58 (81.7%)

 

M1-lym

26 (36.6%)

13 (18.3%)

 

Clinical stage

  

0.018*

IandII

26 (36.6%)

40 (56.3%)

 

III

45 (63.4%)

31 (43.7%)

 

CRT response

27

28

0.001*

PathCRd

4 (29.6%)

16 (67.9%)

 

Less than PathCR

23 (70.4%)

12 (32.1%)

 
  1. aMedian expression level was used as a cutoff to divide the 142 patients into LOC285194 low group (n = 71) and LOC285194 high group (n = 71). bChi-square test. cM1-lym, distant lymph node metastasis. dPathCR, pathologic complete response. *p < 0.05.
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Journal of Translational Medicine

ISSN: 1479-5876

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