Figure 3

Patterns of HBsAg expression detected by immunofluorescence in the liver of patients with HBV-associated HCC. The images illustrate four representative patterns of HBsAg positivity: cytoplasmic diffuse, extended to vast areas of the liver section, found in non-tumorous areas (A) cytoplasmic scattered, found in isolated hepatocytes both in tumoral and non-tumorous areas (B) cytoplasmic spotty, found in limited areas of the hepatocyte cytoplasm both in tumoral and non-tumorous areas (C) membranous, limited to the plasma membrane of hepatocytes within the tumoral areas (D). (Original magnification 63×).