Effect of 10058-F4 on oxidative stress and ATP production in ovarian cancer cells. Hey and SKOV3 cells were treated with F4-10058 at the indicated doses in 96 well plates for 24 hours. Reactive oxygen species (ROS) and ATP production were analyzed by plate reader. Data are presented as the mean of three independent experiments (A, B and C). *p < 0.05 and **p < 0.01, two-sided student t test.