High dose lansoprazole combined with metronomic chemotherapy: a phase I/II study in companion animals with spontaneously occurring tumors

Table 5 Patients characteristics and outcome of 10 pets with advanced cancer treated with metronomic chemotherapy alone

Patient	Age	Sex	Tumor	Prev. treatment	Tumor stage	Outcome (weeks)
Mixed breed	13	FS	Metastatic	Surgery	T₀ N₁ M_X	PD
Mixed breed	13	FS	Anal sac Ca (sublumbar lymph nodes)	Surgery	T₀ N₁ M_X	PD
Poodle	12	MC	Thyroid Ca	Biopsy	T_3B N₀ M_X	PD
Labrador	9	F	Liver CA	Biopsy	T₂ N₀ M_X	PD
Golden retriever	11	MC	Ruptured	Surgery	T₃ N₀ M_X	NED 28
Golden retriever	11	MC	Splenic HSA	Surgery	T₃ N₀ M_X	NED 28
German Shepherd	10	MC	Ruptured	Surgery	T₃ N₀ M_X	NED 20
German Shepherd	10	MC	Splenic HSA	Surgery	T₃ N₀ M_X	NED 20
Boxer	11	FS	Inflammatory mammary Ca	Biopsy	T₄ N₀ M_X	CR 80+
Mixed breed	13	FS	Recurring	Surgery	T₄ N₀ M_X	PD
Mixed breed	13	FS	Inflammatory mammary Ca	Surgery	T₄ N₀ M_X	PD
Boxer	10	FS	Mammary Ca	Biopsy	T_3C N₁ M_X	PD
Doberman	13	FS	Anaplastic mammary Ca (axillary lymph node)	Biopsy	T_3B N₁ M_X	PD
Boxer	11	M C	OSA	Biopsy	T₂ N_X M_X	PR 40

Abbreviations: CA carcinoma, CR complete remission, F female, FS female spayed, M male, MC male castrated, NED no evidence of disease, OSA osteosarcoma, PD progressive disease, PR partial remission.

ISSN: 1479-5876