Skip to main content

Table 2 Stroke patients: correlations between biochemical markers, stroke severity, volume of infarct and stroke outcome

From: Biochemical and inflammatory biomarkers in ischemic stroke: translational study between humans and two experimental rat models

Values of spearman rho correlations:

IL-6

TNF-α

Glutamate

IL-6

IL-6

TNF-α

TNF-α

Glu

Glu

<12 h

72 h

<12 h

72 h

<12 h

72 h

Clinical severity (APACHE II)

All patients

0.261

0.326**

0,130

0,155

−0.076

−0.029

−0.061

0.484**

−0,085

0,068

0.421*

−0.193

Large infarcts

0.630***

0.433

0.244

0.347

−0.052

0.149

−0.369

0.197

−0,821

−0,462

−0.350

−0.727**

Medium infarcts

−0.066

0.241

0.190

0.044

−0.042

−0.007

0.261

0.759**

-

0.400

0.374

0.410

Stroke severity (NIHSS)

All patients

0.068

0.497***

0.312

0.247

0.193

0.261*

-

-

−0.488

−0.488

-

-

Large infarcts

0.247

0.020

0.388

0.433

0.165

−0.013

-

-

−0.866

−0.866

-

-

Medium infarcts

−0.223

0.505***

−0.023

−0.108

0.217

0.371**

-

-

−0.866

−0.866

-

-

Volume of infarct§

All patients

0.207

0.290**

0.476**

0.275

0.120

0.151

Large infarcts

0.398

0.299

0.592*

0364

0.325

0.324

Medium infarcts

0.069

−0.113

0.097

0.178

0.001

0.001

Clinical outcome: 3-months mRS

All patients

0.230

0.444***

0.352*

0.150

0.101

0.006

-

-

0.546

−0.095

-

-

Large infarcts

0.453*

0.455

0.370

0.283

0.235

0.295

-

-

0.105

0.316

-

-

Medium infarcts

0.042

0.273

0.338

0.120

−0.023

−0.080

-

-

0.316

−0.738

-

-

Clinical outcome: 3-months Barthel index

All patients

−0.121

−0.245

−0.152

−0.109

−0.164

−0.017

−0.492*

−0.303

−0.536

−0.009

0.092

0.433*

Large infarcts

−0.366

−0.366

0.119

−0.444

−0.268

0.000

−0.449

−0.338

−0.200

−0.300

−0.570

0.591*

Medium infarcts

−0.053

−0.078

−0.262

0.168

−0.042

0.006

−0.702*

0.025

−0.316

0.738

0.368

−0.495

  1. The numbers in the upper line of each row correspond to stroke patients and the line below to controls.
  2. *P < 0.1; **P < 0.05; ***P < 0.01. Results with P < 0.1 are in bold
  3. §Only stroke patients
  4. APACHE II, Acute Physiology and Chronic Health Evaluation II scale; NIHSS, National Institutes of Health Stroke Scale.