Values of spearman rho correlations:
|
IL-6
|
TNF-α
|
Glutamate
|
---|
IL-6
|
IL-6
|
TNF-α
|
TNF-α
|
Glu
|
Glu
|
---|
<12 h
|
72 h
|
<12 h
|
72 h
|
<12 h
|
72 h
|
---|
Clinical severity (APACHE II)
|
All patients
|
0.261
|
0.326**
|
0,130
|
0,155
|
−0.076
|
−0.029
|
−0.061
|
0.484**
|
−0,085
|
0,068
|
0.421*
|
−0.193
|
Large infarcts
|
0.630***
|
0.433
|
0.244
|
0.347
|
−0.052
|
0.149
|
−0.369
|
0.197
|
−0,821
|
−0,462
|
−0.350
|
−0.727**
|
Medium infarcts
|
−0.066
|
0.241
|
0.190
|
0.044
|
−0.042
|
−0.007
|
0.261
|
0.759**
|
-
|
0.400
|
0.374
|
0.410
|
Stroke severity (NIHSS)
|
All patients
|
0.068
|
0.497***
|
0.312
|
0.247
|
0.193
|
0.261*
|
-
|
-
|
−0.488
|
−0.488
|
-
|
-
|
Large infarcts
|
0.247
|
0.020
|
0.388
|
0.433
|
0.165
|
−0.013
|
-
|
-
|
−0.866
|
−0.866
|
-
|
-
|
Medium infarcts
|
−0.223
|
0.505***
|
−0.023
|
−0.108
|
0.217
|
0.371**
|
-
|
-
|
−0.866
|
−0.866
|
-
|
-
|
Volume of infarct§
|
All patients
|
0.207
|
0.290**
|
0.476**
|
0.275
|
0.120
|
0.151
|
Large infarcts
|
0.398
|
0.299
|
0.592*
|
0364
|
0.325
|
0.324
|
Medium infarcts
|
0.069
|
−0.113
|
0.097
|
0.178
|
0.001
|
0.001
|
Clinical outcome: 3-months mRS
|
All patients
|
0.230
|
0.444***
|
0.352*
|
0.150
|
0.101
|
0.006
|
-
|
-
|
0.546
|
−0.095
|
-
|
-
|
Large infarcts
|
0.453*
|
0.455
|
0.370
|
0.283
|
0.235
|
0.295
|
-
|
-
|
0.105
|
0.316
|
-
|
-
|
Medium infarcts
|
0.042
|
0.273
|
0.338
|
0.120
|
−0.023
|
−0.080
|
-
|
-
|
0.316
|
−0.738
|
-
|
-
|
Clinical outcome: 3-months Barthel index
|
All patients
|
−0.121
|
−0.245
|
−0.152
|
−0.109
|
−0.164
|
−0.017
|
−0.492*
|
−0.303
|
−0.536
|
−0.009
|
0.092
|
0.433*
|
Large infarcts
|
−0.366
|
−0.366
|
0.119
|
−0.444
|
−0.268
|
0.000
|
−0.449
|
−0.338
|
−0.200
|
−0.300
|
−0.570
|
0.591*
|
Medium infarcts
|
−0.053
|
−0.078
|
−0.262
|
0.168
|
−0.042
|
0.006
|
−0.702*
|
0.025
|
−0.316
|
0.738
|
0.368
|
−0.495
|
- The numbers in the upper line of each row correspond to stroke patients and the line below to controls.
- *P < 0.1; **P < 0.05; ***P < 0.01. Results with P < 0.1 are in bold
-
§Only stroke patients
- APACHE II, Acute Physiology and Chronic Health Evaluation II scale; NIHSS, National Institutes of Health Stroke Scale.