A predicted protein, KIAA0247, is a cell cycle modulator in colorectal cancer cells under 5-FU treatment

Table 1 Analyses of mRNA levels of fecal KIAA0247 in clinical features

Features^a		n ^b	Cases with higher mRNA levels of fecal KIAA0247 (>0.4897)	p-value^c
Age (years)
	≤ 66.0	27	11 (40.7%)	0.874
	>66.0	28	12 (42.9%)
Gender
	Male	37	14 (37.8%)	0.290
	Female	19	10 (52.6%)
Dukes' stages
	A+B	28	14 (50.0%)	0.210
	C+D	27	9 (33.3%)
Depth of invasion
	T1+T2	24	14 (58.3%)	0.053
	T3+T4	31	10 (32.3%)
Lymphatic invasion
	N0	32	15 (46.9%)	0.568
	N1+N2+N3	23	9 (39.1%)
Distant metastasis
	No	34	18 (52.9%)	0.058
	Yes	22	6 (27.3%)
Tumor location
	Right	20	6 (30.0%)
	Left	13	6 (46.2%)	0.341
	Rectum	19	10 (52.6%)
CEA (ng/ml)
	≤ 5	28	15 (53.6%)	0.072
	>5	27	8 (29.6%)
CA19-9 (U/ml)
	<37	34	15 (44.1%)	0.371
	≥ 37	19	6 (31.6%)
Differentiation
	Well/moderate	47	22 (46.8%)	0.065
	Poor	5	0 (0%)

^a Median age, 66 years; age range, 40.3-89.5 years; CEA, carcinoembryonic antign; CA19-9, carbohydrate antigen 19-9.
^b Numbers of assessed cases are dependent on the available cases.

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