Figure 4
Reduced proportions of colonic cells in G2/M phase according to KIAA0247expression and 5-FU treatment. The p53-null HCT116 cells (HCT116 p53-/-) with varying KIA0247 expression stained with propidium iodide for evaluation of nuclei fluorescence. The percentages of cell numbers in the cell cycle phases are also shown. shKIAA0247, KIAA0247-silent cells; shLuc, control cells without changing the expression of KIAA0247; overKIAA0247, KIAA0247-overexpressing cells. 5-FU, 5-fluorouracil.