Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization

Table 3 Prognostic impact of miR-155 expression in the total material and histological and nodal status subgroups.

Characteristic	Pts (n)	Pts (%)	Median survival (months)	5-Year survival (%)	Uni-variate P	Multivariate P
Total (n = 335)					0.43	NS
Low	162	48	190	59
High	158	47	84	58
Missing	15	5
SCC (n = 191)						NS
Low	89	47	133	64	0.88
High	98	51	120	68
Missing	4	2
SCC, N0					0.15	NS
Low	59	47	160	79
High	68	53	129	67
SCC, N+					0.034
Low	30	50	49	32
High	30	50	95	68		HR 0.45, CI 95% 0.21-0.96, P = 0.039
AC (n = 95)					0.086
Low	56	62	104	47
High	38	37	71	33		HR 1.87, CI 95% 1.01-3.48, P = 0.047
Missing	1	1
AC, N0					0.37	NS
Low	38	60	117	53
High	25	40	93	47
AC, N+					0.059	NS
Low	18	58	59	32
High	13	42	20	0

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