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Figure 6 | Journal of Translational Medicine

Figure 6

From: Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction

Figure 6

Changes in protein expressions of inflammatory and oxidative markers in kidney after ischemia-reperfusion (IR). A) Remarkably higher expression of intercellular adhesion molecule (ICAM)-1 in IR group than in control and IR + ADMSC group, and notably higher in IR + ADMSC group than in control group; *p < 0.05 between indicated groups. B) Significantly higher expression of nuclear factor (NF)-κB in IR group than in control and IR + ADMSC group, and notably higher in IR + ADMSC group than in control group; *p < 0.04 between indicated groups. C) On day 1 after IR injury, lowest oxidative index, protein carbonyls, in the normal control group without significant difference between IR group and IR + ADMSC group; By day 3 after IR injury, notable increase in oxidative index in IR group compared with control group and IR + ADMSC group. Marked elevation also noted in IR + ADMSC group compared with control group; By day 14 after IR injury, oxidative index remarkably higher in IR group than in control and IR + ADMSC groups without significant difference between IR + ADMSC and control groups. 1) Normal vs. day 1, *p < 0.05 between indicated groups; 2) normal vs. day 3, *p < 0.05 between indicated groups; 3) normal vs. day 14, *p < 0.02 between indicated groups. Symbols (*, †, ‡) indicate significance (at 0.05 level) (by Bonferroni multiple comparison post hoc test) (n = 8 for each group).

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