Figure 3

Histopathological scoring of ischemia-reperfusion (IR)-induced renal injury. H & E staining (200 × in A, B & C and 400 × in D, E & F) of kidney sections in normal, IR, and IR + ADMSC animals, showing notably higher degree of loss of brush border in renal tubules (yellow arrowheads), cast formation (green asterisk), tubular dilatation (blue asterisk), and tubular necrosis (green arrows) in IR without treatment group than in other groups. Also note dilatation of Bowman's capsule (blue arrows) in animals after IR with ADMSC treatment. *p < 0.03 between the indicated groups. Symbols (*, †) indicate significance (at 0.05 level) (by Bonferroni multiple comparison post hoc test). Scale bars in right lower corners represent 50 μm in A, B, & C, and 25 μm in D, E, & F.