Skip to main content

Table 3 Univariate analyses of prognostic factors for survival

From: High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area

Variables No. of patients Cumulative 12-month preogresion free survival rate P Cumulative 2-year overall survival rate P
Age      
   < 50 22 49.0% 0.725 50.0% 0.152
   50 35 68.6%   68.0%  
Gender      
   male 55 61.5% 0.878 65.2% 0.553
   female 2 50.0%   50.0%  
Site      
   oral cavity 24 41.7%   45.5% 0.093
   oropharynx 21 66.7% 0.101 66.6%  
   Hypopharynx/larynx 12 81.8% 0.035* 83.3%  
Stage      
   IVa 10 80.0% 0.119 90.0% 0.049*
   IVb 47 57.2%   54.7%  
T stage      
   0-2 6 66.7% 0.396 66.7% 0.694
   3-4 51 60.5%   60.3%  
N stage      
   negative 12 50.0% 0.837 72.9% 0.350
   positive 45 57.3%   57.8%  
Radiation      
   6000 cGy 20 55.0% 0.304 55.0% 0.412
   > 6000 cGy 37 64.5%   64.1%  
Alcohol      
   never 11 63.6% 1.000 63.6% 0.754
   yes 46 60.6%   64.8%  
Smoking      
   never 9 66.7% 0.614 66.7% 0.679
   yes 48 60.1%   60.0%  
Betel nuts      
   never 20 70.0% 0.638 74.0% 0.123
   yes 37 56.3%   54.1%  
ERCC1      
   low expression 31 73.7% < 0.001* 74.2% 0.023*
   high expression 26 42.3%   44.4%