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Table 1 Tumor growth by 2 mm

From: High dose intermittent sorafenib shows improved efficacy over conventional continuous dose in renal cell carcinoma

Treatment Vehicle (N = 9) CD continuous (N = 11) HD intermittent (N = 11) CD intermittent (N = 8) HD continuous (N = 4)
Days to grow by 2 mm 6.2 ± 1.9 9.2 ± 1.7 12.9 ± 3.3 7.1 ± 1.7 16.8 ± 3.9
  1. High dose intermittent therapy stabilized tumors longer as seen by the difference in the number of days for the tumors to increase by 2 mm in size. All arms are significantly different (P < 0.05) except the conventional dose (CD) continuous vs CD intermittent, the CD intermittent vs vehicle and the high dose (HD) intermittent vs HD continuous.