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Figure 3 | Journal of Translational Medicine

Figure 3

From: The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism

Figure 3

Time-dependent effects of PF-03882845 on plasma aldosterone AUC. PF-03882845 resulted in a time-dependent increase in plasma aldosterone AUC corrected to vehicle in Spontaneously Hypertensive Rats (SHR). Statistical analysis indicated an overall significant effect of time (P = 0.0454 by one-way ANOVA). There was no significance between any two groups when analyzed with Tukey's Multiple Comparison Test. Data are shown as mean + SEM.

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